Impact of left ventricular ejection fraction on 10-year mortality after percutaneous coronary intervention or coronary artery bypass grafting

Abstract Backgrounds The impact on vital prognosis at very long-term of percutaneous coronary intervention (PCI) and artery bypass grafting (CABG) in patients with reduced ejection fraction (EF) remains to be elucidated. Objective To investigate the left ventricular (LVEF) 10-year mortality after PCI CABG SYNTAX trial. Methods In SYNTAXES study, 1,800 randomized were categorized into three groups according current guidelines; (1) EF (rEF; LVEF ≤40%), (2) mildly (mrEF; 41–49%), (3) preserved (pEF; ≥50%). primary endpoint was all-cause mortality. Event rate up 10 years estimated Kaplan-Meier method, log-rank test performed examine differences among subgroups. score 2020 (SS-2020) compared between (LVEF <50%) ≥50%) order better refine their respective personalized assess cross-validation value risk score. Results population stratified as rEF (n=168), mrEF (n=179), pEF (n=1453). Ten-year 44.0% vs. 31.8% 22.6% (P<0.001), rEF, pEF, respectively. significant interaction not identified classification treatment (P = 0.183). there a tendency toward higher group than (52.9% vs 39.6%, P=0.054), no (36.0% 28.6%, P=0.273) (23.9% 22.2%, P=0.275). According SS-2020, relatively safe modality revascularization 37.8% <50%). ≥50%), proportion eligible predicted equipoise 57.5%. Conclusion could an important factor for determining presenting complex disease. Calculation individualized using SS-2020 may viable option decision-making. Funding Acknowledgement Type funding sources: None.